The Italian model debuted on the catwalk of the Chanel firm, in exclusive in their Spring / Summer 2016 fashion show.
She has also worked for the firms Furla, Juicy Couture, Polo Ralph Lauren, DKNY or Diesel, among many others and it is usual at the Dolce & Gabbana fashion shows and campaigns.
Scelsi has been on the cover of numerous magazines such as L'Officiel Italy, WSJ, Vogue Portugal, Vogue Latino, Elle Italy, Elle France, Woman, and Marie Claire Italy.
She is currently on the "The Money Girls" list of models.com.
In 2019, she became the new face of the makeup campaign Chanel S/S 2019 by Karim Sadli with the top models Vittoria Ceretti, Liu Wen and Imaan Hammam.
She has lately starred in various magazine covers such as Elle Italia, L’Officiel Brasil walked the Off-White S/S 20 runway, among others.